Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915239 | 0.81 | KDM4E (0.33) | — | |
| SCHEMBL28060151 | 0.75 | PSIP1 (0.31) | — | |
| SCHEMBL27725335 | 0.74 | HDAC1 (0.53) | — | |
| SCHEMBL27744017 | 0.74 | CFTR (0.32) | — | |
| SCHEMBL27725303 | 0.72 | HDAC1 (0.43) | — | |
| SCHEMBL27520313 | 0.72 | CA1 (0.41) | CA12CA1CA2CA4CA6 | |
| SCHEMBL27736333 | 0.71 | TSHR (0.35) | CA12CA1CA2CA4CA6 | |
| SCHEMBL28060197 | 0.69 | HDAC1 (0.32) | CA12CA1CA2CA4CA6 | |
| SCHEMBL27591138 | 0.68 | — | — | |
| SCHEMBL28777481 | 0.68 | HDAC3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492429-A | Heteroaryl inhibitors of SUMO activating enzyme | MILLENNIUM PHARM INC | 2016-04-13 | — | — | CN | disclosed |