Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27591140 | 0.84 | ALDH1A1 (0.37) | SMN1; SMN2PKM | |
| SCHEMBL28060198 | 0.81 | CA12 (0.30) | — | |
| SCHEMBL28044543 | 0.74 | ALDH1A1 (0.34) | SMN1; SMN2PKM | |
| SCHEMBL27520313 | 0.70 | CA1 (0.41) | KDM4ESMN1; SMN2HDAC3HDAC6NCOR2 | |
| SCHEMBL27915236 | 0.70 | DHCR7 (0.36) | KDM4ESMN1; SMN2PKMHDAC3HDAC6 | |
| SCHEMBL27736333 | 0.69 | TSHR (0.35) | SMN1; SMN2 | |
| SCHEMBL27591138 | 0.69 | — | — | |
| SCHEMBL27622086 | 0.68 | KDM4E (0.36) | KDM4ESMN1; SMN2HDAC3HDAC6NCOR2 | |
| SCHEMBL22290714 | 0.67 | PKM (0.45) | KDM4ESMN1; SMN2PKMHDAC6 | |
| SCHEMBL28777481 | 0.66 | HDAC3 (0.35) | HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103237800-B | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP. (JP) | 2015-10-21 | — | — | CN | disclosed |
| CN-103237800-A | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP | 2013-08-07 | — | — | CN | disclosed |