Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | CTSG | P08311 | 2/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.30 |
| ▸ | CMA1 | P23946 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300520 | 0.80 | DGAT1 (0.46) | DGAT1KCNN4ALDH1A1LMNAKMT2A | |
| SCHEMBL4463173 | 0.76 | DGAT1 (0.50) | DGAT1KCNN4POLBALDH1A1TSHR | |
| SCHEMBL25946813 | 0.73 | FFAR3 (0.38) | ALDH1A1KMT2ATSHR | |
| SCHEMBL21687493 | 0.73 | DGAT1 (0.41) | DGAT1KCNN4ALDH1A1LMNAKMT2A | |
| SCHEMBL988428 | 0.73 | KCNN4 (0.41) | DGAT1KCNN4ALDH1A1LMNAKMT2A | |
| SCHEMBL3169320 | 0.73 | DGAT1 (0.37) | DGAT1POLBALDH1A1NPSR1HPGD | |
| SCHEMBL17611270 | 0.73 | DGAT1 (0.37) | DGAT1ALDH1A1KMT2AGAA | |
| SCHEMBL27820854 | 0.73 | DGAT1 (0.37) | DGAT1NPSR1HPGDTSHRMAPK1 | |
| SCHEMBL1854077 | 0.71 | — | — | |
| SCHEMBL27580351 | 0.71 | DGAT1 (0.45) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583501-A | Compounds and compositions for treating conditions associated with LPA receptor activity | 罗特斯生物公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-104540826-B | Spiro-fused piperidine derivatives useful as inhibitors of extrarenal potassium channels | 默沙东公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107074843-A | heteroaromatic compounds and their use as dopamine D1 ligands | 辉瑞公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-105324376-B | Heteroaromatics and its purposes as dopamine D 1 part | 辉瑞大药厂 | 2017-06-23 | — | — | CN | disclosed |
| CN-105612162-A | Thiazolopyrimidinones as modulators of NMDA receptor activity | HOFFMANN LA ROCHE | 2016-05-25 | — | — | CN | disclosed |