Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988428 | 0.86 | KCNN4 (0.41) | DGAT1KCNN4ALDH1A1SRCLMNA | |
| SCHEMBL21687493 | 0.86 | DGAT1 (0.41) | DGAT1KCNN4ALDH1A1SRCLMNA | |
| SCHEMBL117832 | 0.81 | — | — | |
| SCHEMBL27622606 | 0.81 | — | — | |
| SCHEMBL28060314 | 0.80 | DGAT1 (0.37) | DGAT1KCNN4ALDH1A1SRCLMNA | |
| SCHEMBL5613155 | 0.78 | — | — | |
| SCHEMBL10954143 | 0.78 | KCNN4 (0.42) | DGAT1KCNN4ALDH1A1SRCLMNA | |
| SCHEMBL98576 | 0.77 | — | — | |
| SCHEMBL9263129 | 0.77 | — | — | |
| SCHEMBL5870536 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619397-A1 | SALT-INDUCIBLE KINASES (SIK) INHIBITORS AND METHODS OF USES THEREOF | Insilico Medicine IP Limited (HK) | 2025-09-24 | — | — | EP | disclosed |
| WO-2025014051-A1 | ULTRAVIOLET-BLOCKING ADHESIVE COMPOSITION, METHOD FOR PREPARING ADHESIVE RESIN BY USING SAME, AND ADHESIVE FILM MANUFACTURED USING SAME | 서울대학교산학협력단 | 2025-01-16 | — | — | WO | disclosed |
| WO-2024104441-A1 | SALT-INDUCIBLE KINASES (SIK) INHIBITORS AND METHODS OF USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-05-23 | — | — | WO | disclosed |
| CN-112839931-B | 1,2,3, 4-tetrahydroquinoxaline derivative, and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| US-20220009894-A1 | 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2022-01-13 | — | — | US | disclosed |
| CN-112839931-A | 1,2,3, 4-tetrahydroquinoxaline derivative and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-100551944-C | Polymer solid electrolyte | NIPPON SODA CO (JP) | 2009-10-21 | — | — | CN | disclosed |
| US-7579401-B2 | Block polymer of polymethoxypolyethylene glycol monomethyl methacrylate and polystyrene; LiClO4 a lithium salt as electrolyte; living copolymerization, block polymerization; excellent thermal characteristics, physical characteristics, and ionic conductivity; secondary batteries | NIPPON SODA CO., LTD. (JP) | 2009-08-25 | — | — | US | disclosed |
| EP-1627736-B1 | Method of manufacturing light sensitive planographic printing plates and method of using the same | KONICA MINOLTA MED & GRAPHIC (JP) | 2008-10-01 | — | — | EP | disclosed |
| EP-1553117-B1 | SOLID POLYMER ELECTROLYTE | NIPPON SODA CO (JP) | 2007-01-17 | — | — | EP | disclosed |
| US-20050256256-A1 | Block polymer of polymethoxypolyethylene glycol monomethyl methacrylate and polystyrene; LiClO4 a lithium salt as electrolyte; living copolymerization, block polymerization; excellent thermal characteristics, physical characteristics, and ionic conductivity; secondary batteries | NIPPON SODA CO., LTD (JP) | 2005-11-17 | — | — | US | disclosed |
| CN-1668662-A | Solid polymer electrolyte | NIPPON SODA CO (JP) | 2005-09-14 | — | — | CN | disclosed |
| EP-1553117-A1 | SOLID POLYMER ELECTROLYTE | NIPPON SODA CO., LTD. (JP) | 2005-07-13 | — | — | EP | disclosed |
| US-5132475-A | Quaternary ammonium fluoride catalyzed halogenation of carbon acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-21 | — | — | US | disclosed |
| US-4609396-A | GRASSES IN BROADLEAF CROPS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| US-4368068-A | PRE- AND POSTEMERGENCE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-11 | — | — | US | disclosed |
| EP-0042750-A2 | Quinoxalinyloxy ethers as selective weed control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009894-A1 | 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | RORA, RORB, RORC | DGAT1 944/4885KCNN4 4112/4885ALDH1A1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.