Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219902 | 0.85 | TTR (0.47) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL18780838 | 0.84 | TTR (0.53) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL6325919 | 0.83 | TTR (0.56) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL6325921 | 0.83 | TTR (0.56) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL16127516 | 0.81 | TTR (0.75) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL23449276 | 0.80 | EGFR (0.66) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL13207350 | 0.79 | ALDH1A1 (0.52) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL2824309 | 0.79 | ALDH1A1 (0.52) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL2824311 | 0.79 | ALDH1A1 (0.52) | TTRCES1RAB9ATRPA1NPC1 | |
| SCHEMBL18780877 | 0.79 | MAPT (0.52) | TTRCES1RAB9ATRPA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503688-B | A kind of method of the halogenation trifluoromethylation reaction of alkene | 武汉大学 | 2018-03-13 | — | — | CN | disclosed |
| CN-105503688-A | Method for conducting halogenated trifluoromethylation reaction on alkene | UNIV WUHAN | 2016-04-20 | — | — | CN | disclosed |