Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27939943 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL27751339 | 0.86 | CA12 (0.51) | POLBCA12CA1CA2CA7 | |
| SCHEMBL27939921 | 0.85 | BLM (0.53) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28289049 | 0.84 | ALDH1A1 (0.50) | POLBL3MBTL1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28045771 | 0.83 | ALDH1A1 (0.44) | POLBALDH1A1SMN1; SMN2MEN1HTT | |
| SCHEMBL27814971 | 0.82 | MEN1 (0.48) | HSP90AA1HSD11B1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27786432 | 0.81 | CA12 (0.55) | POLBCA12CA1CA2CA7 | |
| SCHEMBL27787706 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL3093877 | 0.79 | MEN1 (0.68) | POLBCA12CA1CA2CA7 | |
| SCHEMBL6985975 | 0.79 | CA12 (0.71) | POLBCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105399698-A | Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines | GUANGDONG HEC PHARMACEUTICAL | 2016-03-16 | — | — | CN | disclosed |