Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 10/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060545 | 0.80 | POLB (0.51) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17180311 | 0.79 | HTR2A (0.57) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL27787732 | 0.79 | HTR2A (0.49) | HTR2AHTR2CKCNH2 | |
| SCHEMBL9660142 | 0.77 | TSHR (0.68) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL27731418 | 0.77 | LTA4H (0.52) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL27758338 | 0.76 | HSD11B1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HTR2AGAA | |
| SCHEMBL9871356 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL27758590 | 0.75 | KMT2A (0.37) | ALDH1A1SMN1; SMN2CYP2D6MEN1KMT2A | |
| SCHEMBL7462619 | 0.75 | ALDH1A1 (0.71) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10369554 | 0.74 | ALDH1A1 (0.60) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102838546-B | Pyrazole derivatives as modulators of 5-ht2a serotonin receptor useful for treatment of disorders related thereto | ARENA PHARM INC | 2015-07-15 | — | — | CN | disclosed |
| CN-102838546-A | Pyrazole derivatives as modulators of 5-ht2a serotonin receptor useful for treatment of disorders related thereto | ARENA PHARM INC | 2012-12-26 | — | — | CN | disclosed |
| CN-101611013-B | As 5-HT2APyrazole derivatives of serotonin receptor modulators for the treatment of disorders related thereto | ARENA PHARM INC | 2012-09-05 | — | — | CN | disclosed |
| CN-101611013-A | As 5-HT2APyrazole derivatives of serotonin receptor modulators for the treatment of disorders related thereto | ARENA PHARM INC (US) | 2009-12-23 | — | — | CN | disclosed |