Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16056008 | 0.83 | ERN1 (0.43) | ERN1ALDH1A1PTGS1MAPTSLC6A4 | |
| SCHEMBL505506 | 0.78 | PTGS1 (0.42) | ERN1ALDH1A1PTGS1MAPTPTGS2 | |
| SCHEMBL16669880 | 0.77 | ALDH1A1 (0.40) | ERN1ALDH1A1DRD1PTGS1MAPT | |
| SCHEMBL16616213 | 0.76 | ERN1 (0.34) | ERN1ALDH1A3ALDH1A1MAPTPTGS2 | |
| SCHEMBL25319381 | 0.74 | MAPT (0.36) | ERN1ALDH1A1DRD1PTGS1MAPT | |
| SCHEMBL30482786 | 0.74 | MAPT (0.36) | ERN1ALDH1A1DRD1PTGS1MAPT | |
| SCHEMBL21413070 | 0.74 | ALDH1A3 (0.38) | ERN1ALDH1A3ALDH1A1MAPTCYP1A2 | |
| SCHEMBL18003978 | 0.74 | ERN1 (0.47) | ERN1ALDH1A3ALDH1A1MAPTCYP1A2 | |
| SCHEMBL38651684 | 0.73 | ALDH1A3 (0.37) | ERN1ALDH1A3MAPTLMNACYP1A2 | |
| SCHEMBL18489256 | 0.73 | ALDH1A3 (0.37) | ERN1ALDH1A3MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612158-A | Antagonists of somatostatin receptor subtype 5 (sstr5) | TAKEDA PHARMACEUTICALS CO | 2016-05-25 | — | — | CN | disclosed |