SCHEMBL28060648

SCHEMBL28060648

O=[N+]([O-])c1ccc(C2CCCCN2)c(S(=O)(=O)O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.42
SLC6A3 Q01959 1/20 0.39
NT5E P21589 1/20 0.39
CHRNB4 P30926 2/20 0.37
CHRNA3 P32297 2/20 0.37
HTR1A P08908 1/20 0.37
SLC18A3 Q16572 1/20 0.37
ALDH1A1 P00352 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HPGD P15428 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
LMNA P02545 1/20 0.37
EPHX2 P34913 1/20 0.36
TBXA2R P21731 3/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11613339 0.96 HSP90AA1 (0.40) HSP90AA1NT5ECHRNB4CHRNA3HTR1A
SCHEMBL27992014 0.79 ALDH1A1 (0.46) HSP90AA1SLC6A3ALDH1A1SMN1; SMN2KMT2A
SCHEMBL28397099 0.77 ERN1 (0.46) HSP90AA1SLC6A3CHRNB4CHRNA3HTR1A
SCHEMBL27470794 0.75 HSD17B10 (0.47) HSP90AA1SLC6A3CHRNB4CHRNA3HTR1A
SCHEMBL11589948 0.75 HSP90AA1 (0.61) HSP90AA1CHRNB4CHRNA3ALDH1A1SMN1; SMN2
SCHEMBL11612361 0.75 MEN1 (0.40) NT5EALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL28923834 0.74 ALDH1A1 (0.47) HSP90AA1ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL28168557 0.73 ERN1 (0.47) HSP90AA1CHRNB4CHRNA3HTR1AALDH1A1
SCHEMBL11631660 0.72 SLC6A3 (0.47) SLC6A3SLC18A3ALDH1A1SMN1; SMN2MEN1
SCHEMBL9097323 0.72 HSP90AA1 (0.65) HSP90AA1NT5ECHRNB4CHRNA3SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120035427-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-23 CN disclosed
CN-119894486-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-25 CN disclosed
CN-119855579-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-18 CN disclosed
CN-119836282-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-15 CN disclosed
CN-119317420-A Use of a composition comprising an alkyl carbonate or an alkylene carbonate for removing colour from previously dyed keratin hair fibres without damaging the keratin hair fibres 欧莱雅 2025-01-14 CN disclosed
CN-119317424-A Method for removing colour from previously dyed keratin hair fibres 欧莱雅 2025-01-14 CN disclosed
CN-118414142-A Method for removing makeup from keratin fibres that have been pretreated with a composition comprising a photocrosslinkable polymer 莱雅公司 2024-07-30 CN disclosed
CN-118414143-A Composition comprising a photo-crosslinkable polymer having hydrophobic groups and a colorant 莱雅公司 2024-07-30 CN disclosed
CN-117120027-A Hair coloring composition comprising at least one (poly) carbodiimide compound and at least one non-carboxylic acid anionic thickener 欧莱雅 2023-11-24 CN disclosed
CN-117120026-A Method for coloring hair keratin fibers comprising the application of a composition comprising at least one (poly) carbodiimide compound and a composition comprising at least one associative polymer and a specific compound 欧莱雅 2023-11-24 CN disclosed
CN-117015369-A Method for coloring hair keratin fibers comprising the application of a composition comprising at least one (poly) carbodiimide compound and a composition comprising at least one associative polymer and a specific compound 欧莱雅 2023-11-07 CN disclosed
CN-116997320-A Hair colouring composition comprising at least one (poly) carbodiimide compound and at least one compound comprising at least one hydroxyl function 欧莱雅 2023-11-03 CN disclosed
CN-116847820-A Method for removing the color of pre-colored hair keratin fibers 欧莱雅 2023-10-03 CN disclosed
CN-115461032-A Process for treating keratin fibres using a composition comprising at least one alkoxysilane of formula (I), at least one non-amino silicone of formula (II) having a weight-average molecular weight of less than or equal to 1500g/mol and at least one colorant 莱雅公司 2022-12-09 CN disclosed
CN-105828882-B Packaging article comprising an envelope and an anhydrous dye composition comprising a direct dye, use thereof and process for dyeing keratin fibres 莱雅公司 2022-09-30 CN disclosed
CN-114340588-A Composition comprising at least one alkoxysilane of formula (I), at least one alkoxysilane of formula (II), at least one non-amino silicone and optionally a pigment and/or direct dye 莱雅公司 2022-04-12 CN disclosed
CN-112888485-A Cosmetic compositions, methods and uses thereof 莱雅公司 2021-06-01 CN disclosed
CN-111032007-A Method for dyeing keratin fibres using at least one direct dye and at least one fluorescent dye chosen from disulfides, thiols and protected thiols 莱雅公司 2020-04-17 CN disclosed
CN-105828882-A Packaging article comprising an envelope and an anhydrous dye composition comprising a direct dye, use thereof and process for dyeing keratin fibres 莱雅公司 2016-08-03 CN disclosed