Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 8/20 | 0.53 |
| ▸ | PIM1 | P11309 | 3/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758061 | 0.84 | L3MBTL1 (1.00) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL27189175 | 0.84 | L3MBTL1 (0.54) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL689416 | 0.82 | L3MBTL1 (0.72) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL27591329 | 0.82 | L3MBTL1 (0.72) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL11286218 | 0.81 | MAPT (0.60) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL10746638 | 0.81 | L3MBTL1 (0.70) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL10746814 | 0.81 | L3MBTL1 (0.70) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL10544113 | 0.80 | MAPT (0.58) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL10544120 | 0.80 | MAPT (0.58) | L3MBTL1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL8879890 | 0.78 | L3MBTL1 (0.66) | L3MBTL1KDM4EHSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016944-B | N-(2-(amine methyl) phenyl) thiazole-4-carboxamide derivative and preparation method thereof and application | SHANDONG UNIVERSITY (CN) | 2016-05-18 | — | — | CN | claimed |
| CN-104016944-B | N-(2-(amine methyl) phenyl) thiazole-4-carboxamide derivative and preparation method thereof and application | SHANDONG UNIVERSITY (CN) | 2016-05-18 | — | — | CN | disclosed |