Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689416 | 0.84 | L3MBTL1 (0.72) | L3MBTL1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL27591329 | 0.84 | L3MBTL1 (0.72) | L3MBTL1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL28060720 | 0.84 | L3MBTL1 (0.72) | L3MBTL1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL10746638 | 0.82 | L3MBTL1 (0.70) | L3MBTL1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL10746814 | 0.82 | L3MBTL1 (0.70) | L3MBTL1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL1808047 | 0.82 | L3MBTL1 (0.70) | L3MBTL1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL10694480 | 0.82 | L3MBTL1 (0.69) | L3MBTL1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL10694485 | 0.82 | L3MBTL1 (0.69) | L3MBTL1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL1809197 | 0.81 | L3MBTL1 (0.68) | L3MBTL1KDM4EMAPTKMT2APOLB | |
| SCHEMBL7906267 | 0.81 | L3MBTL1 (0.68) | L3MBTL1KDM4EMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2639229-B9 | Thiazole Derivative and use thereof as VAP-1 Inhibitor | R TECH UENO LTD (JP) | 2015-08-05 | — | — | EP | claimed |
| EP-2639229-B1 | Thiazole Derivative and use thereof as VAP-1 Inhibitor | R TECH UENO LTD (JP) | 2014-11-26 | — | — | EP | claimed |
| EP-2252604-B1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R TECH UENO LTD (JP) | 2014-01-08 | — | — | EP | claimed |
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | claimed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | claimed |
| EP-2743271-B1 | PIM KINASE INHIBITORS AND PREPARATION METHOD AND USE IN MEDICINAL MANUFACTURE THEREOF | JIKAI BIOSCIENCES INC (CN) | 2017-05-31 | — | — | EP | disclosed |
| EP-3002278-B1 | GUANIDINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-9556160-B2 | Guanidine compound | ASTELLAS PHARMA INC. (JP) | 2017-01-31 | — | — | US | disclosed |
| US-9556160-B2 | Guanidine compound | ASTELLAS PHARMA INC. (JP) | 2017-01-31 | — | — | US | disclosed |
| EP-2797885-B1 | NEW AZETIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2016-08-10 | — | — | EP | disclosed |
| EP-2695881-B1 | GUANIDINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-04-27 | — | — | EP | disclosed |
| EP-3002278-A1 | GUANIDINE COMPOUND | Astellas Pharma Inc. (JP) | 2016-04-06 | — | — | EP | disclosed |
| US-5543528-A | Imidazolines | SANOFI (FR) | 1996-08-06 | — | — | US | disclosed |
| US-5434167-A | Angiotensin II antagonists | SANOFI (FR) | 1995-07-18 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | disclosed |
| EP-0562936-A1 | Imidazolines N-substituted by a biphenylmethyl group, their preparation, the pharmaceutical compositions containing them | SANOFI (FR) | 1993-09-29 | — | — | EP | disclosed |
| US-RE29003-E | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3957758-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3956323-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-11 | — | — | US | disclosed |