SCHEMBL28060725

SCHEMBL28060725

CCCCC(Cl)[N+](=O)[O-].O=[N+]([O-])S(=O)(=O)Cl

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
CA2 P00918 1/20 0.33
VCAM1 P19320 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5199027 0.88
SCHEMBL5138846 0.73 ALDH1A1 (0.37) ALDH1A1CA2VCAM1
SCHEMBL2694685 0.67
SCHEMBL1170388 0.66 ALDH1A1 (0.46) ALDH1A1CA2
SCHEMBL9452613 0.66 ALDH1A1 (0.46) ALDH1A1CA2
SCHEMBL12862825 0.65 ALDH1A1 (0.45) ALDH1A1CA2
SCHEMBL11573573 0.65 ALDH1A1 (0.40) ALDH1A1CA2
SCHEMBL1236221 0.65
SCHEMBL1170855 0.65
SCHEMBL2800523 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503730-A Pyrazole derivative and preparation method and application thereof UNIV SHANDONG 2016-04-20 CN disclosed