Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060725 | 0.73 | ALDH1A1 (0.47) | ALDH1A1CA2VCAM1 | |
| SCHEMBL9059431 | 0.70 | — | — | |
| SCHEMBL1415215 | 0.70 | TP53 (0.34) | ALDH1A1CA2TP53CA1CA7 | |
| SCHEMBL5199027 | 0.70 | — | — | |
| SCHEMBL9452613 | 0.69 | ALDH1A1 (0.46) | ALDH1A1CA2CA1 | |
| SCHEMBL1170388 | 0.69 | ALDH1A1 (0.46) | ALDH1A1CA2CA1 | |
| SCHEMBL5888772 | 0.69 | TP53 (0.37) | ALDH1A1CA2TP53CA1CA7 | |
| SCHEMBL27289489 | 0.69 | TP53 (0.37) | CA2TP53CA1CA9 | |
| SCHEMBL1170855 | 0.67 | — | — | |
| SCHEMBL6113068 | 0.67 | TP53 (0.45) | CA2TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858632-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KOEHLER PAPER SE (DE) | 2023-01-18 | — | — | EP | disclosed |
| CN-109790108-B | Thermosensitive recording material | 奥古斯特科勒纸厂欧洲公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-108699008-B | Sulfonamide derivatives and pharmaceutical compositions containing the same | EA制药株式会社 | 2021-10-08 | — | — | CN | disclosed |
| CN-101006052-B | Pyrrole derivatives as pharmaceutical agents | EXELIXIS INC | 2013-11-06 | — | — | CN | disclosed |
| US-7393873-B2 | Arylsulfonamide derivatives | MERCK & CO., INC. (US) | 2008-07-01 | — | — | US | disclosed |
| US-20060142612-A1 | Arylsulfonamide derivatives | MERCK SHARP & DOHME CORP. | 2006-06-29 | — | — | US | disclosed |
| EP-1643960-A2 | ARYLSULFONAMIDE DERIVATIVES | Merck & Co., Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005004810-A2 | ARYLSULFONAMIDE DERIVATIVES | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142612-A1 | Arylsulfonamide derivatives | BDKRB1, BDKRB2, LTB4R2 | ALDH1A1 3142/4885CA2 3840/4885TP53 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.