SCHEMBL28060760

SCHEMBL28060760

O=C(O)c1c(Br)cc2ccccc2c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
CYP1A2 P05177 2/20 0.58
HPGD P15428 2/20 0.58
HSD17B10 Q99714 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
GLA P06280 1/20 0.58
CYP2C19 P33261 1/20 0.58
LDHA P00338 1/20 0.49
POLB P06746 1/20 0.46
GPR35 Q9HC97 1/20 0.46
ME2 P23368 1/20 0.46
ME1 P48163 1/20 0.46
ME3 Q16798 1/20 0.46
RXFP1 Q9HBX9 1/20 0.45
CDC25B P30305 1/20 0.45
CYP2D6 P10635 1/20 0.44
CYP3A4 P08684 1/20 0.44
STAT6 P42226 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1694540 0.85 MEN1 (0.68) MEN1KMT2ACYP1A2HPGDHSD17B10
SCHEMBL4637660 0.84 MEN1 (0.60) MEN1KMT2ACYP1A2HPGDHSD17B10
SCHEMBL245378 0.81 CYP1A2 (0.62) MEN1KMT2ACYP1A2HPGDHSD17B10
SCHEMBL31149178 0.81 CYP1A2 (0.62) MEN1KMT2ACYP1A2HPGDHSD17B10
SCHEMBL28535619 0.81 KMT2A (0.56) MEN1KMT2ACYP1A2HPGDHSD17B10
SCHEMBL28283411 0.80 MEN1 (0.48) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL5375009 0.80 MEN1 (0.60) MEN1KMT2ACYP1A2HPGDHSD17B10
SCHEMBL538425 0.79 HPGD (0.58) MEN1KMT2ACYP1A2HPGDHSD17B10
SCHEMBL2791213 0.79 CYP1A2 (0.58) MEN1KMT2ACYP1A2HPGDHSD17B10
SCHEMBL9273082 0.78 MEN1 (0.58) MEN1KMT2ACYP1A2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105378554-B Color electrophoretic display 伊英克公司 2019-01-22 CN disclosed
CN-107922403-A 2, 3-dihydro-4H-1, 3-benzoxazin-4-one derivatives as modulators of cholinergic muscarinic M1 receptors 武田药品工业株式会社 2018-04-17 CN disclosed
CN-106977479-A Novel amine compound and organic light-emitting device including the same SFC株式会社 2017-07-25 CN disclosed
CN-106588531-A Spiro ring organic photoelectric material, preparation method and applications thereof 中节能万润股份有限公司 2017-04-26 CN disclosed
CN-105378554-A Colored electrophoretic displays E INK CORP 2016-03-02 CN disclosed