SCHEMBL245378

SCHEMBL245378

O=C(O)c1c(O)cc2ccccc2c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.62
KDM4E B2RXH2 1/20 0.62
MEN1 O00255 1/20 0.62
ALDH1A1 P00352 1/20 0.62
GLA P06280 1/20 0.62
HPGD P15428 1/20 0.62
CYP2C19 P33261 1/20 0.62
KMT2A Q03164 1/20 0.62
HSD17B10 Q99714 1/20 0.62
APP P05067 1/20 0.53
LDHA P00338 1/20 0.52
TRPM4 Q8TD43 1/20 0.50
POLB P06746 1/20 0.49
GPR35 Q9HC97 1/20 0.49
ME2 P23368 1/20 0.48
ME1 P48163 1/20 0.48
ME3 Q16798 1/20 0.48
CDC25B P30305 1/20 0.47
THRB P10828 1/20 0.47
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31149178 1.00 CYP1A2 (0.62) CYP1A2KDM4EMEN1ALDH1A1GLA
Hydrochloric Acid SCHEMBL11313207 0.87 CYP1A2 (0.66) CYP1A2KDM4EMEN1ALDH1A1GLA
SCHEMBL770722 0.86 CYP1A2 (0.70) CYP1A2KDM4EMEN1ALDH1A1GLA
SCHEMBL3273261 0.85 KDM4E (0.53) CYP1A2KDM4EMEN1ALDH1A1GLA
SCHEMBL29779946 0.85 CYP1A2 (0.68) CYP1A2KDM4EMEN1ALDH1A1GLA
SCHEMBL88986 0.85 CYP1A2 (0.68) CYP1A2KDM4EMEN1ALDH1A1GLA
SCHEMBL5375009 0.83 MEN1 (0.60) CYP1A2KDM4EMEN1ALDH1A1GLA
SCHEMBL2941699 0.83 MAPT (0.49) CYP1A2KDM4EMEN1ALDH1A1GLA
SCHEMBL19691146 0.83 TRPM4 (0.48) CYP1A2KDM4EMEN1ALDH1A1GLA
SCHEMBL538425 0.81 HPGD (0.58) CYP1A2KDM4EMEN1ALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-113329993-A Use of polyhydroxy aromatic compounds for treating fibrous substrates based on amino acids 迈图高新材料有限责任公司 2021-08-31 CN claimed
CN-102665738-B Prophylactic composition for influenza infection MEIJI CO LTD 2015-07-01 CN claimed
US-9027647-B2 Treatment fluids containing a biodegradable chelating agent and methods for use thereof HALLIBURTON ENERGY SERVICES, INC. (US) 2015-05-12 US claimed
CN-103290077-A Method for efficiently producing vitamin K2 by flavobacterium HEFEI INST PHYSICAL SCI CAS 2013-09-11 CN claimed
US-20130095542-A1 ENGINEERED MICROORGANISMS AND INTEGRATED PROCESS FOR PRODUCING N-PROPANOL, PROPYLENE AND POLYPROPYLENE BRASKEM S.A. (BR) 2013-04-18 US claimed
CN-102008460-B Anti-allergic agent MEIJI DAIRIES CORP 2012-09-19 CN claimed
EP-2464735-A1 MICROORGANISMS AND PROCESS FOR PRODUCING N-PROPANOL Braskem S.A. (BR) 2012-06-20 EP claimed
CN-102166018-A Method of stabilizing 1,4-dihydroxy-2-naphthoic acid MEIJI DAIRIES CORP 2011-08-31 CN claimed
US-7997342-B2 Subterranean treatment fluids comprising viscoelastic surfactant gels HALLIBURTON ENERGY SERVICES, INC. (US) 2011-08-16 US claimed
CN-1860236-A Process for producing 1,4-dihydoxy-2-naphthoic acid MEIJI DAIRIES CORP (JP) 2006-11-08 CN claimed
CN-1820741-A Process for producing 1,4-dihydroxy-2-naphthoic acid MEIJI DAIRIES CORP (JP) 2006-08-23 CN claimed
EP-1422256-B1 THERMOTROPIC LIQUID-CRYSTAL POLYMER UENO SEIYAKU OYO KENKYUJO KK (JP) 2006-08-02 EP claimed
CN-1764627-A Method for stabilizing 1, 4-dihydroxy-2-naphthoic acid MEIJI DAIRIES CORP (JP) 2006-04-26 CN claimed
CN-1539019-A Method for producing 1, 4-dihydroxy-2-naphthoic acid ͬ�Ϳ�ҵ��ʽ���� 2004-10-20 CN claimed
CN-1501964-A The use of aromatic compounds as phase directors and particle size reducers for quinacridone pigments �������⻯ѧƷ�ع����޹�˾ 2004-06-02 CN claimed
EP-1370614-A1 THE USE OF AROMATIC COMPOUNDS AS PHASE DIRECTORS AND PARTICLE SIZE REDUCERS FOR QUINACRIDONE PIGMENTS Ciba SC Holding AG (CH) 2003-12-17 EP claimed
US-6626990-B2 Using aromatic- or heteraromatic-compounds having at least one hydroxyl or keto group bonded to the ring, with the oxidation of corresponding dihydroquinacridone salts CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-30 US claimed
US-20020161232-A1 Use of aromatic compounds as phase directors and particle size reducers for quinacridone pigments CIBA SPECIALTY CHEMICALS CORP. 2002-10-31 US claimed
WO-2002077104-A1 THE USE OF AROMATIC COMPOUNDS AS PHASE DIRECTORS AND PARTICLE SIZE REDUCERS FOR QUINACRIDONE PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020161232-A1 Use of aromatic compounds as phase directors and particle size reducers for quinacridone pigments QDPR, POLR2H, POLR2E CYP1A2 192/4885KDM4E 3124/4885MEN1 4591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.