Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4389413 | 0.85 | HCAR2 (0.47) | LMNAHCAR2CYP2C9DAO | |
| SCHEMBL4389421 | 0.85 | HCAR2 (0.47) | LMNAHCAR2CYP2C9DAO | |
| SCHEMBL7890266 | 0.81 | CES2 (0.41) | LMNAHCAR2 | |
| SCHEMBL7890262 | 0.81 | CES2 (0.41) | LMNAHCAR2 | |
| SCHEMBL4395717 | 0.79 | TTR (0.41) | LMNAHCAR2CYP1A2CYP2C9 | |
| SCHEMBL4395722 | 0.79 | TTR (0.41) | LMNAHCAR2CYP1A2CYP2C9 | |
| SCHEMBL14038839 | 0.75 | — | — | |
| SCHEMBL24737413 | 0.75 | TTR (0.46) | LMNAHCAR2 | |
| SCHEMBL29136928 | 0.75 | TTR (0.46) | LMNAHCAR2 | |
| SCHEMBL18737420 | 0.73 | PYGL (0.41) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585544-A | Trans-substituted alkene derivative, medicine composition containing same and medical application of trans-substituted alkene derivative | XIXI HOSPITAL OF HANGZHOU | 2016-05-18 | — | — | CN | disclosed |