Carbazole

Carbazole

SCHEMBL28060913

O=[N+]([O-])c1ccccc1.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
LMNA P02545 3/20 0.64
CTSV O60911 1/20 0.60
CTSL P07711 1/20 0.60
GPR3 P46089 1/20 0.56
HSD17B10 Q99714 1/20 0.56
GABRP O00591 2/20 0.54
GABRD O14764 2/20 0.54
GABRA1 P14867 2/20 0.54
GABRB1 P18505 2/20 0.54
GABRG2 P18507 2/20 0.54
GABRB3 P28472 2/20 0.54
GABRA5 P31644 2/20 0.54
GABRA3 P34903 2/20 0.54
GABRA2 P47869 2/20 0.54
GABRB2 P47870 2/20 0.54
GABRA4 P48169 2/20 0.54
GABRE P78334 2/20 0.54
GABRA6 Q16445 2/20 0.54
GABRG1 Q8N1C3 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbazole SCHEMBL27552113 0.94 CTSV (0.67) ALDH1A1LMNACTSVCTSLGPR3
Carbazole SCHEMBL27971512 0.85 ALDH1A1 (0.70) ALDH1A1LMNACTSVCTSLGPR3
SCHEMBL30272741 0.83 CTSV (0.79) ALDH1A1LMNACTSVCTSLGABRP
SCHEMBL6008321 0.83 CTSV (0.69) CTSVCTSLGABRPGABRDGABRA1
SCHEMBL30272742 0.83 CTSV (0.79) ALDH1A1LMNACTSVCTSLGABRP
SCHEMBL30272743 0.83 CTSV (0.79) ALDH1A1LMNACTSVCTSLGABRP
SCHEMBL151534 0.83 CTSV (0.79) ALDH1A1LMNACTSVCTSLGABRP
Nitrobenzene SCHEMBL29397531 0.82 ALDH1A1 (0.94) ALDH1A1LMNAHSD17B10HPGDATM
Carbazole SCHEMBL28988608 0.81 ALDH1A1 (0.64) ALDH1A1LMNACTSVCTSLGPR3
Nitrobenzene SCHEMBL15525745 0.80 ALDH1A1 (1.00) ALDH1A1LMNAHSD17B10HPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105585519-A Preparation method of novel Schiff base micromolecular compound UNIV QILU TECHNOLOGY 2016-05-18 CN claimed
CN-105542165-B A kind of N-shaped electrochromic polymeric compounds material and preparation method thereof 华南理工大学 2019-04-09 CN disclosed
CN-105585519-A Preparation method of novel Schiff base micromolecular compound UNIV QILU TECHNOLOGY 2016-05-18 CN disclosed