Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.61 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027004 | 1.00 | NQO2 (0.61) | NQO2NR0B1MEN1KMT2AMAPT | |
| 3-Formylindole SCHEMBL7494141 | 0.85 | CYP2A6 (0.68) | NQO2NR0B1MEN1KMT2AMAPT | |
| SCHEMBL10489040 | 0.81 | CYP2A6 (0.69) | NQO2NR0B1MEN1KMT2AMAPT | |
| SCHEMBL30309878 | 0.78 | NQO2 (0.60) | NQO2NR0B1MEN1KMT2AMAPT | |
| SCHEMBL18128880 | 0.78 | NQO2 (0.60) | NQO2NR0B1MEN1KMT2AMAPT | |
| SCHEMBL2026175 | 0.78 | NQO2 (0.60) | NQO2NR0B1MEN1KMT2AMAPT | |
| SCHEMBL28026492 | 0.77 | IMPDH2 (0.44) | NQO2NR0B1MEN1KMT2AMAPT | |
| SCHEMBL9000553 | 0.75 | MAPT (0.65) | NQO2MEN1KMT2AMAPTHPGD | |
| SCHEMBL3174845 | 0.75 | ALDH1A1 (0.76) | NQO2MEN1KMT2AMAPTHPGD | |
| SCHEMBL9665295 | 0.75 | MAPT (0.65) | NQO2MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104840461-A | Use of trans-1-(indole-3-yl)-2-(quinoline-4-yl)-ethylene derivative and composition | SHANGHAI INST MATERIA MEDICA | 2015-08-19 | — | — | CN | claimed |
| CN-114907514-A | Multifunctional fiber and preparation method and application thereof | 北京洁尔爽高科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-105385011-A | TPV composition and automobile anti-collision strip | Jiaxing boer plastic co ltd | 2016-03-09 | — | — | CN | disclosed |
| CN-104840461-A | Use of trans-1-(indole-3-yl)-2-(quinoline-4-yl)-ethylene derivative and composition | SHANGHAI INST MATERIA MEDICA | 2015-08-19 | — | — | CN | disclosed |