Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916156 | 0.86 | HDAC4 (0.50) | KMT2AHDAC4HDAC6PKMCYP2C9 | |
| SCHEMBL1415222 | 0.74 | GAA (0.44) | KMT2APKMCYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL363895 | 0.73 | ALDH1A1 (0.40) | SOAT1KMT2AHDAC4HDAC6PKM | |
| SCHEMBL4066379 | 0.73 | — | — | |
| SCHEMBL5239683 | 0.71 | MAPT (0.38) | KMT2AHDAC4HDAC6ALDH1A1GAA | |
| SCHEMBL13450125 | 0.71 | NPC1 (0.41) | KMT2AALDH1A1GAAGFERMEN1 | |
| Hydrochloric Acid SCHEMBL28052061 | 0.70 | SOAT1 (0.47) | SOAT1KMT2ACYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL27814361 | 0.69 | KMT2A (0.41) | KMT2ACYP2C9ALDH1A1GAAGFER | |
| SCHEMBL22430810 | 0.69 | TDP1 (0.56) | KMT2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL11496498 | 0.69 | SOAT1 (0.41) | SOAT1KMT2ACYP2C9ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803252-B | Be used for the treatment of indole amides derivative and the related compound thereof of neurodegenerative disorders | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2016-05-25 | — | — | CN | disclosed |