Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29175598 | 0.84 | HTT (0.50) | KMT2ASMN1; SMN2HTTTDP1ELANE | |
| SCHEMBL28167146 | 0.84 | ELANE (0.51) | KMT2ASMN1; SMN2HTTTDP1ELANE | |
| SCHEMBL5813373 | 0.84 | ELANE (0.51) | KMT2ASMN1; SMN2HTTTDP1ELANE | |
| SCHEMBL30878614 | 0.84 | LMNA (0.51) | KMT2ASMN1; SMN2MEN1LMNAHTR2C | |
| SCHEMBL24605352 | 0.81 | KMT2A (0.68) | KMT2ASMN1; SMN2HTTTDP1MEN1 | |
| SCHEMBL27947111 | 0.81 | KMT2A (0.68) | KMT2ASMN1; SMN2HTTTDP1MEN1 | |
| SCHEMBL12370833 | 0.81 | KMT2A (0.68) | KMT2ASMN1; SMN2HTTTDP1MEN1 | |
| SCHEMBL2741099 | 0.81 | KMT2A (0.68) | KMT2ASMN1; SMN2HTTTDP1MEN1 | |
| SCHEMBL4630575 | 0.81 | HTR2C (0.62) | KMT2ASMN1; SMN2HTTTDP1ELANE | |
| SCHEMBL10291941 | 0.78 | KMT2A (0.75) | KMT2ASMN1; SMN2HTTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803252-B | Be used for the treatment of indole amides derivative and the related compound thereof of neurodegenerative disorders | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2016-05-25 | — | — | CN | disclosed |