Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182288 | 0.72 | TSHR (0.42) | TSHR | |
| SCHEMBL261995 | 0.71 | TSHR (0.37) | TSHR | |
| SCHEMBL28652971 | 0.68 | TSHR (0.48) | TSHR | |
| SCHEMBL9842007 | 0.63 | TSHR (0.48) | TSHR | |
| SCHEMBL1865097 | 0.63 | — | — | |
| SCHEMBL25763520 | 0.63 | TSHR (0.48) | TSHR | |
| SCHEMBL13615583 | 0.63 | TSHR (0.48) | TSHR | |
| SCHEMBL1578780 | 0.62 | — | — | |
| SCHEMBL2113184 | 0.61 | — | — | |
| SCHEMBL10293082 | 0.61 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803252-B | Be used for the treatment of indole amides derivative and the related compound thereof of neurodegenerative disorders | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2016-05-25 | — | — | CN | disclosed |