Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL27997998 | 0.82 | ALDH1A1 (0.58) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL30777936 | 0.82 | GAA (0.51) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL28573106 | 0.82 | GAA (0.51) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL154847 | 0.81 | ALDH1A1 (0.64) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL28228752 | 0.81 | ALDH1A1 (0.56) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8197602 | 0.79 | ALDH1A1 (0.62) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL5352931 | 0.79 | ALDH1A1 (0.53) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL10934941 | 0.77 | KMT2A (0.45) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL30075088 | 0.77 | ALDH1A1 (0.55) | KMT2AKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL28795494 | 0.77 | ALDH1A1 (0.55) | KMT2AKDM4EGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481769-A | Benzo(c)acridine derivative, and preparation method and use thereof | UNIV GUANGXI CHINESE MEDICINE | 2016-04-13 | — | — | CN | disclosed |