Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.38 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061472 | 1.00 | BTK (0.49) | BTKPRCPSMN1; SMN2RECQLSCN4A | |
| SCHEMBL28061492 | 0.93 | SMN1; SMN2 (0.49) | BTKPRCPSMN1; SMN2RECQLSCN4A | |
| SCHEMBL27913885 | 0.86 | BTK (0.51) | BTKSMN1; SMN2SCN4ACA1CA2 | |
| SCHEMBL7050477 | 0.83 | SCN4A (0.43) | BTKSMN1; SMN2SCN4AALDH1A1NUDT14 | |
| SCHEMBL27896216 | 0.82 | BTK (0.49) | BTKSMN1; SMN2SCN4ACA1CA2 | |
| SCHEMBL27568293 | 0.80 | BTK (0.45) | BTKSMN1; SMN2SCN4AALDH1A1NUDT14 | |
| SCHEMBL28762063 | 0.80 | BTK (0.42) | BTKSCN4ACA1CA2HRH3 | |
| SCHEMBL28762061 | 0.80 | BTK (0.42) | BTKSCN4ACA1CA2HRH3 | |
| SCHEMBL28942737 | 0.79 | SCN4A (0.35) | BTKPRCPSMN1; SMN2SCN4ACA1 | |
| SCHEMBL28942739 | 0.79 | SCN4A (0.35) | BTKPRCPSMN1; SMN2SCN4ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481862-A | Novel inhibitors of FLT3 kinase and uses thereof | HEFEI INST PHYSICAL SCI CAS | 2016-04-13 | — | — | CN | claimed |