Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 4/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061472 | 0.93 | BTK (0.49) | SMN1; SMN2RECQLSCN4ABTKPRCP | |
| SCHEMBL28061471 | 0.93 | BTK (0.49) | SMN1; SMN2RECQLSCN4ABTKPRCP | |
| SCHEMBL27896216 | 0.86 | BTK (0.49) | SMN1; SMN2SCN4ABTKCA1CA2 | |
| SCHEMBL27913885 | 0.82 | BTK (0.51) | SMN1; SMN2SCN4ABTKCA1CA2 | |
| SCHEMBL6640044 | 0.81 | BTK (0.46) | SCN4ABTKALDH1A1 | |
| SCHEMBL7047879 | 0.78 | SCN4A (0.47) | SCN4ABTK | |
| SCHEMBL7050477 | 0.78 | SCN4A (0.43) | SMN1; SMN2SCN4ABTKALDH1A1 | |
| SCHEMBL23217070 | 0.78 | BTK (0.52) | SCN4ABTK | |
| SCHEMBL5803668 | 0.78 | DRD4 (0.54) | SCN4A | |
| SCHEMBL5803839 | 0.78 | HCK (0.46) | SCN4ABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481862-A | Novel inhibitors of FLT3 kinase and uses thereof | HEFEI INST PHYSICAL SCI CAS | 2016-04-13 | — | — | CN | claimed |
| CN-105481862-A | Novel inhibitors of FLT3 kinase and uses thereof | HEFEI INST PHYSICAL SCI CAS | 2016-04-13 | — | — | CN | disclosed |