Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061025 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL28093154 | 0.74 | TP53 (0.39) | — | |
| SCHEMBL5501308 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL4375225 | 0.70 | CA12 (0.47) | SMN1; SMN2 | |
| SCHEMBL17842409 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL25744924 | 0.67 | PDE2A (0.30) | — | |
| SCHEMBL16553574 | 0.65 | NPC1 (0.45) | SMN1; SMN2PLK1 | |
| SCHEMBL9244967 | 0.65 | TERT (0.43) | SMN1; SMN2 | |
| SCHEMBL666590 | 0.64 | — | — | |
| SCHEMBL31041847 | 0.64 | NPC1 (0.63) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105517553-A | Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use | LEXICON PHARMACEUTICALS INC | 2016-04-20 | — | — | CN | disclosed |