SCHEMBL28093154

SCHEMBL28093154

FC(F)(F)CCn1cccc1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19073983 0.84 TP53 (0.36) TP53
SCHEMBL28061568 0.74 SMN1; SMN2 (0.36)
SCHEMBL27910344 0.71 TP53 (0.53) TP53
SCHEMBL8887346 0.71 TP53 (0.31) TP53
SCHEMBL19992033 0.69 LMNA (0.38)
SCHEMBL24045337 0.67 TP53 (0.34) TP53
SCHEMBL29213145 0.67 TP53 (0.34) TP53
SCHEMBL20465806 0.65 TP53 (0.48) TP53
SCHEMBL691481 0.65 TP53 (0.48) TP53
SCHEMBL16553574 0.65 NPC1 (0.45) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107176953-A substituted benzaldehyde compound and its method for increasing tissue oxygenation 全球血液疗法公司 2017-09-19 CN disclosed
CN-105980386-A Pyrazolo compounds and uses thereof 基因泰克公司 2016-09-28 CN disclosed