SCHEMBL28061737

SCHEMBL28061737

C=C1C(=O)N(c2ccccc2)C(=O)N1c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.46
GAA P10253 3/20 0.45
ALDH1A1 P00352 5/20 0.42
NPSR1 Q6W5P4 2/20 0.42
CES2 O00748 1/20 0.42
BCHE P06276 1/20 0.42
CES1 P23141 1/20 0.42
GRK5 P34947 1/20 0.41
TYRO3 Q06418 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HSD17B10 Q99714 1/20 0.39
PKM P14618 1/20 0.39
TLR9 Q9NR96 1/20 0.39
HSPA1A P0DMV8 1/20 0.39
PABPC1 P11940 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28061712 0.98 MGLL (0.45) MGLLGAAALDH1A1NPSR1CES2
SCHEMBL21415451 0.84 MGLL (0.48) MGLLGAAALDH1A1NPSR1CES2
SCHEMBL2851080 0.84 MGLL (0.56) MGLLGAAALDH1A1NPSR1CES2
SCHEMBL27658196 0.82 MGLL (0.47) MGLLGAAALDH1A1NPSR1CES2
SCHEMBL2928174 0.79 GAA (0.57) MGLLGAAALDH1A1NPSR1CES2
SCHEMBL11182628 0.78 MGLL (0.62) MGLLGAAALDH1A1NPSR1CES2
SCHEMBL11410726 0.75 MGLL (0.52) MGLLGAAALDH1A1NPSR1CES2
SCHEMBL16280099 0.73 MGLL (0.62) MGLLGAAALDH1A1NPSR1CES2
SCHEMBL25880393 0.72 MEN1 (0.52) GAAALDH1A1NPSR1CES2BCHE
SCHEMBL11604846 0.72 F2 (0.68) MGLLGAAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601156-A Concrete efficient water reducer and preparation method thereof XIAO COUNTY LIANGYU CONCRETE CO LTD 2016-05-25 CN claimed
CN-108329268-A A kind of synthetic method of hydantoin derivatives 淮海工学院 2018-07-27 CN disclosed