SCHEMBL2928174

SCHEMBL2928174

O=C1C(=O)N(c2ccccc2)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.57
ALDH1A1 P00352 3/20 0.57
NPSR1 Q6W5P4 2/20 0.57
CES2 O00748 1/20 0.57
BCHE P06276 1/20 0.57
CES1 P23141 1/20 0.57
MGLL Q99685 1/20 0.52
GRK5 P34947 1/20 0.45
TYRO3 Q06418 1/20 0.45
DYRK1B Q9Y463 1/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
PKM P14618 1/20 0.42
TLR9 Q9NR96 1/20 0.42
HSPA1A P0DMV8 1/20 0.42
PABPC1 P11940 1/20 0.42
ESR1 P03372 1/20 0.42
ELANE P08246 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2851080 0.90 MGLL (0.56) GAAALDH1A1NPSR1CES2BCHE
SCHEMBL6360785 0.85 ALDH1A1 (0.48) GAAALDH1A1NPSR1CES2BCHE
SCHEMBL11182628 0.84 MGLL (0.62) GAAALDH1A1NPSR1CES2BCHE
SCHEMBL21415451 0.81 MGLL (0.48) GAAALDH1A1NPSR1CES2BCHE
SCHEMBL28061737 0.79 MGLL (0.46) GAAALDH1A1NPSR1CES2BCHE
SCHEMBL16280099 0.78 MGLL (0.62) GAAALDH1A1NPSR1CES2BCHE
SCHEMBL11608974 0.78 MEN1 (0.62) GAAALDH1A1MGLLMEN1KMT2A
SCHEMBL11604846 0.78 F2 (0.68) GAAALDH1A1MGLLMEN1KMT2A
SCHEMBL28061712 0.78 MGLL (0.45) GAAALDH1A1NPSR1CES2BCHE
SCHEMBL23806076 0.76 ITGA4 (0.45) GAAALDH1A1NPSR1CES2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1317013-B1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEM CORP (JP) 2017-03-15 EP disclosed
EP-1312335-B1 Cosmetic compositions containing aminosilicone and a conditioning agent and their use OREAL (FR) 2010-08-11 EP disclosed
US-6942948-B2 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-09-13 US disclosed
US-20030165733-A1 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2003-09-04 US disclosed
EP-1312335-A2 Cosmetic compositions containing aminosilicone and a conditioning agent and their use L'OREAL (FR) 2003-05-21 EP disclosed
EP-0243116-A2 Optical sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-10-28 EP disclosed