Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | COMT | P21964 | 2/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903919 | 0.88 | CCR1 (0.48) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL2062319 | 0.84 | KDM4E (0.73) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL29930654 | 0.84 | KDM4E (0.73) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL19232758 | 0.81 | PTGES (0.42) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL16541599 | 0.81 | PTGES (0.42) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL28928675 | 0.80 | KDM4E (0.67) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL21180300 | 0.80 | GAA (0.50) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL28295235 | 0.79 | KDM4E (0.55) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL16128904 | 0.79 | PTGES (0.51) | MAPTKDM4EALDH1A1USP2HPGD | |
| SCHEMBL2062423 | 0.79 | TNKS (0.49) | MAPTKDM4ENPC1COMTNOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601676-B | A kind of ruthenium complex and its application | 广东药科大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-105601676-A | Ruthenium complex and application thereof | UNIV GUANGDONG PHARM | 2016-05-25 | — | — | CN | disclosed |