Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | IDO1 | P14902 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | TDO2 | P48775 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | PDE5A | O76074 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930654 | 0.96 | KDM4E (0.73) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL2062319 | 0.96 | KDM4E (0.73) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL28295235 | 0.85 | KDM4E (0.55) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL30516133 | 0.80 | KDM4E (1.00) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL20211621 | 0.80 | KDM4E (1.00) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL28061757 | 0.80 | MEN1 (0.52) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL21180300 | 0.79 | GAA (0.50) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL21180250 | 0.78 | PTGES (0.49) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL21180297 | 0.78 | PTGES (0.73) | KDM4EGAAALDH1A1IDO1MEN1 | |
| SCHEMBL19233099 | 0.78 | PTGES (0.49) | KDM4EGAAALDH1A1IDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851717-B | ruthenium-LHRH coupled diagnosis and treatment probe for targeted ovarian cancer and preparation method and application thereof | 广东药科大学 | 2022-10-25 | — | — | CN | disclosed |