Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.73 |
| ▸ | HTR6 | P50406 | 12/20 | 0.71 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10016358 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1RAB9ACREBBPHTR6 | |
| SCHEMBL28692486 | 0.83 | HTT (0.53) | SMN1; SMN2ALDH1A1RAB9ACREBBPHTR6 | |
| SCHEMBL29441740 | 0.79 | MAPT (0.62) | SMN1; SMN2ALDH1A1RAB9ACREBBPHTR6 | |
| SCHEMBL5026889 | 0.78 | HTR2C (0.57) | SMN1; SMN2ALDH1A1RAB9ACREBBPHTR6 | |
| SCHEMBL13650811 | 0.77 | HPGD (0.55) | SMN1; SMN2ALDH1A1RAB9ACREBBPPKM | |
| SCHEMBL5123188 | 0.77 | HTR2C (0.56) | SMN1; SMN2ALDH1A1RAB9ACREBBPHTR6 | |
| SCHEMBL12499681 | 0.77 | PIK3CA (0.73) | SMN1; SMN2ALDH1A1RAB9ACREBBPHRH4 | |
| SCHEMBL30192927 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1RAB9ACREBBPHRH4 | |
| SCHEMBL1443593 | 0.75 | PIK3CA (0.61) | SMN1; SMN2ALDH1A1RAB9ACREBBPPKM | |
| SCHEMBL1396153 | 0.75 | PKM (0.58) | SMN1; SMN2ALDH1A1RAB9ACREBBPPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503754-A | 2-amino-4-benzyl-6-morpholine-1,3,5-triazine and preparing and application thereof | UNIV ZHEJIANG | 2016-04-20 | — | — | CN | claimed |
| CN-105503754-B | The triazine of 2 amino, 4 benzyl, 6 morpholine 1,3,5 and its preparation and application | 浙江大学 | 2017-11-17 | — | — | CN | disclosed |
| CN-105503754-A | 2-amino-4-benzyl-6-morpholine-1,3,5-triazine and preparing and application thereof | UNIV ZHEJIANG | 2016-04-20 | — | — | CN | disclosed |
| CN-105503754-A | 2-amino-4-benzyl-6-morpholine-1,3,5-triazine and preparing and application thereof | UNIV ZHEJIANG | 2016-04-20 | — | — | CN | disclosed |
| CN-105503754-A | 2-amino-4-benzyl-6-morpholine-1,3,5-triazine and preparing and application thereof | UNIV ZHEJIANG | 2016-04-20 | — | — | CN | disclosed |