Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619754 | 0.86 | HTR6 (0.56) | HTTHTR6HRH4TSHRALDH1A1 | |
| SCHEMBL28061822 | 0.83 | SMN1; SMN2 (0.73) | HTTHTR6HRH4TSHRALDH1A1 | |
| SCHEMBL12110270 | 0.77 | SMN1; SMN2 (0.50) | HTTHRH4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17358224 | 0.75 | L3MBTL1 (0.49) | HTR6HRH4TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9619196 | 0.75 | KDM4E (0.58) | HTTHRH4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12110268 | 0.75 | KMT2A (0.56) | HTTHRH4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14146764 | 0.75 | HTR6 (0.45) | HTR6ALDH1A1SMN1; SMN2RAB9ACREBBP | |
| SCHEMBL14146760 | 0.75 | PIK3CA (0.45) | HTR6TSHRALDH1A1GAAPIK3CA | |
| SCHEMBL11862853 | 0.74 | HTT (0.56) | HTTTSHRALDH1A1SMN1; SMN2PKM | |
| SCHEMBL17548980 | 0.73 | ALDH1A1 (0.47) | HTR6HRH4TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437167-B | Aromatic vinyl substituted triazine compound and preparation method and application thereof | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |