SCHEMBL28061848

SCHEMBL28061848

NC(=O)c1cc(S(=O)(=O)O)ccc1S(=O)(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
HSD17B10 Q99714 4/20 0.49
KDM4E B2RXH2 3/20 0.49
HPGD P15428 1/20 0.49
CASP6 P55212 2/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NT5E P21589 3/20 0.42
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
CA2 P00918 3/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA7 P43166 2/20 0.40
CA14 Q9ULX7 2/20 0.40
LMNA P02545 1/20 0.39
TIMP3 P35625 1/20 0.38
S1PR3 Q99500 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28061801 0.85 ALDH1A1 (0.44) ALDH1A1HSD17B10KDM4EHPGDCASP6
SCHEMBL6865738 0.84 ALDH1A1 (0.52) ALDH1A1HSD17B10KDM4EHPGDCASP6
Ammonia Solution, Strong SCHEMBL7095002 0.82 ALDH1A1 (0.50) ALDH1A1HSD17B10KDM4EHPGDCASP6
SCHEMBL17857831 0.82 HSD17B10 (0.65) ALDH1A1HSD17B10KDM4EHPGDCASP6
SCHEMBL7460497 0.81 ALDH1A1 (0.68) ALDH1A1HSD17B10KDM4EHPGDCASP6
SCHEMBL1806291 0.81 ALDH1A1 (0.53) ALDH1A1HSD17B10KDM4EHPGDCASP6
SCHEMBL30873374 0.81 ALDH1A1 (0.53) ALDH1A1HSD17B10KDM4EHPGDCASP6
SCHEMBL11344526 0.79 ALDH1A1 (0.61) ALDH1A1HSD17B10KDM4EHPGDNT5E
SCHEMBL11344523 0.79 ALDH1A1 (0.61) ALDH1A1HSD17B10KDM4EHPGDCASP6
SCHEMBL1805024 0.79 MAPK1 (0.55) ALDH1A1HSD17B10KDM4EHPGDNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105602279-A Porphyrazine coloring matter, ink composition, recording method, and colored object NIPPON KAYAKU KK 2016-05-25 CN disclosed