Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238094 | 0.84 | ALDH1A1 (0.47) | ALDH1A1CYP2D6SOAT1HDAC3HDAC4 | |
| SCHEMBL17212355 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP2D6SOAT1HDAC3HDAC4 | |
| SCHEMBL264599 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP2D6SOAT1HDAC3HDAC4 | |
| SCHEMBL10063796 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP2D6SOAT1HDAC3HDAC4 | |
| SCHEMBL866981 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP2D6SOAT1HDAC3HDAC4 | |
| SCHEMBL12308922 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP2D6SOAT1HDAC3HDAC4 | |
| SCHEMBL13047819 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CYP2D6SOAT1HDAC3HDAC4 | |
| SCHEMBL15134282 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL12222648 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP2D6MAPTCA12CA1 | |
| SCHEMBL12087618 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133960-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-20100315588-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317817-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |