Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107954 | 0.86 | EPHX1 (0.62) | PPARGPPARALMNASLC6A2SLC6A4 | |
| SCHEMBL9895055 | 0.85 | PPARG (0.41) | PPARGPPARALMNAEPHX2 | |
| SCHEMBL9896075 | 0.85 | PPARG (0.41) | PPARGPPARALMNAEPHX2 | |
| SCHEMBL7437418 | 0.81 | KMT2A (0.58) | PPARGPPARALMNAALDH1A1HPGD | |
| SCHEMBL28743175 | 0.80 | AKR1B1 (0.52) | PPARGCYP2C19LMNASLC6A2SLC6A4 | |
| SCHEMBL21540121 | 0.80 | KDM4E (0.44) | PPARGPPARALMNASMN1; SMN2HPGD | |
| SCHEMBL7384644 | 0.79 | PPARG (0.57) | PPARGPPARAALDH1A1HPGDCTBP2 | |
| SCHEMBL8057075 | 0.79 | UBE2N (0.47) | PPARGCYP2C19SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL10852993 | 0.79 | CHRM1 (0.55) | CYP2C19SLC6A2SLC6A4HPGD | |
| SCHEMBL22394880 | 0.79 | PPARG (0.51) | PPARGPPARACYP2C19SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431510-A | Organic compounds | GIVAUDAN SA | 2016-03-23 | — | — | CN | disclosed |