Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPA3 | P15088 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419792 | 0.94 | PPARG (0.64) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL7273958 | 0.91 | PPARG (0.50) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL27304316 | 0.91 | PPARG (0.50) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL7299030 | 0.89 | CPA1 (0.61) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL27784429 | 0.86 | CPA3 (0.63) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL7437418 | 0.86 | KMT2A (0.58) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL28005647 | 0.85 | PPARG (0.54) | PPARGPPARAHPGDALDH1A1CTBP2 | |
| SCHEMBL7382016 | 0.85 | PPARG (0.48) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL7367331 | 0.84 | PPARG (0.45) | PPARGCYP1A2PPARAHPGDALDH1A1 | |
| SCHEMBL7367328 | 0.84 | PPARG (0.45) | PPARGCYP1A2PPARAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610177-A | Acylated amino acids as endothelin antagonists | WARNER-LAMBERT COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| US-4870183-A | RENIN INHIBITORS, HYPOTENSIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0252727-A1 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-01-13 | — | — | EP | disclosed |