Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9896075 | 1.00 | PPARG (0.41) | PPARGPPARAPTGS2AKR1C3AKR1C2 | |
| SCHEMBL9894964 | 0.85 | ESR1 (0.45) | PPARGPPARAPTGS2LMNAEPHX2 | |
| SCHEMBL28062032 | 0.85 | PPARG (0.49) | PPARGPPARALMNAEPHX2 | |
| SCHEMBL9896010 | 0.76 | EPHX2 (0.51) | PTGS2AKR1C3AKR1C2EPHX2CA2 | |
| SCHEMBL4482850 | 0.76 | AKR1C3 (0.47) | AKR1C3AKR1C2LMNAEPHX2GRM4 | |
| SCHEMBL9895000 | 0.75 | SLC1A1 (0.48) | PPARGPPARAPTGS2AKR1C3EPHX2 | |
| SCHEMBL9894874 | 0.75 | NPC1 (0.42) | PTGS2 | |
| SCHEMBL9896932 | 0.75 | NPC1 (0.42) | PTGS2 | |
| SCHEMBL9894873 | 0.75 | NPC1 (0.42) | PTGS2 | |
| SCHEMBL9895033 | 0.75 | GAA (0.38) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | P2RX7, P2RX3, P2RX2 | PPARG 283/4885PPARA 399/4885PTGS2 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.