Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541808 | 1.00 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541106 | 1.00 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541372 | 0.99 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541861 | 0.95 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL6852709 | 0.94 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5673772 | 0.90 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1260811 | 0.90 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL176508 | 0.89 | THRB (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541396 | 0.89 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541480 | 0.89 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105611951-A | Antioxidative prosthetic member | KYOCERA MEDICAL CORP | 2016-05-25 | — | — | CN | disclosed |