Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541808 | 0.94 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541106 | 0.94 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28062034 | 0.94 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541372 | 0.93 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5673772 | 0.90 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1260811 | 0.90 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL541861 | 0.89 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1260101 | 0.88 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL31216396 | 0.84 | TSHR (0.40) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL176508 | 0.84 | THRB (0.38) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220227954-A1 | POLYMERIC SURFACE HAVING REDUCED BIOMOLECULE ADHESION TO THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | OAKTREE FUND ADMINISTRATION, LLC | 2022-07-21 | — | — | US | disclosed |
| US-11248100-B2 | Polymeric surface having reduced biomolecule adhesion to thermoplastic articles of such substrate | SIO2 MEDICAL PRODUCTS, INC (US) | 2022-02-15 | — | — | US | disclosed |
| EP-3862384-A2 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| US-20180334545-A1 | POLYMERIC SURFACE HAVING REDUCED BIOMOLECULE ADHESION TO THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | OAKTREE FUND ADMINISTRATION, LLC | 2018-11-22 | — | — | US | disclosed |
| EP-3377565-A1 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| US-6828028-B1 | Having surface treated with copolymer of such as ring opened glycidyl methacrylate and 2-(methacryloyloxy)ethyl-2-(tri-methylammonio)ethylphosphate; lubricity, blood compatible, safe, stable, durable | NOF CORPORATION (JP) | 2004-12-07 | — | — | US | disclosed |