Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171114 | 0.83 | GABBR2 (0.53) | MAPTCYP2D6SRCGABBR2GABBR1 | |
| Hydrogen Sulfide SCHEMBL28282419 | 0.81 | GABBR2 (0.52) | MAPTCYP2D6SRCGABBR2GABBR1 | |
| SCHEMBL109205 | 0.80 | LMNA (0.53) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL13270955 | 0.79 | CYP2C19 (0.51) | ALDH1A1CYP2D6SRCGABBR2GABBR1 | |
| SCHEMBL3068269 | 0.79 | KCNA5 (0.50) | MTNR1AMTNR1BALDH1A1MAPTKMT2A | |
| SCHEMBL15793307 | 0.79 | GAA (0.41) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL13559962 | 0.78 | GABBR2 (0.53) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL29067280 | 0.78 | LMNA (0.52) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL30438111 | 0.78 | LMNA (0.52) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| Anisole SCHEMBL10424847 | 0.78 | HTT (0.50) | MTNR1AMTNR1BKMT2ACYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136433-B | Antiviral compounds with a heterotricyclic moiety | LUPIN LTD. (IN) | 2016-05-04 | — | — | CN | disclosed |