Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062106 | 0.80 | GLA (0.48) | CA1CA2CA9CA12PSMD10 | |
| SCHEMBL22588443 | 0.79 | KMT2A (0.52) | CA1CA2CA9CA12GRM4 | |
| SCHEMBL19859664 | 0.75 | GRM4 (0.51) | CA1CA2CA9CA12GRM4 | |
| SCHEMBL28229562 | 0.72 | PTGS2 (0.57) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL21807392 | 0.72 | FBP1 (0.53) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL12615300 | 0.70 | MEN1 (0.40) | CA2CA9KMT2AMEN1FBP1 | |
| SCHEMBL28396678 | 0.70 | KMT2A (0.55) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL12424564 | 0.69 | CA12 (0.43) | CA1CA2CA9CA12GRM4 | |
| SCHEMBL22558313 | 0.69 | MAPT (0.56) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL21875183 | 0.69 | FBP1 (0.49) | CA1CA2CA9CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218917-B | Preparation method of (1-aminovinyl) phosphine oxide derivative | 广西大学 | 2020-08-18 | — | — | CN | claimed |
| CN-108218917-B | Preparation method of (1-aminovinyl) phosphine oxide derivative | 广西大学 | 2020-08-18 | — | — | CN | disclosed |
| CN-104130204-B | A kind of method preparing N-alkylsulfonyl-Isosorbide-5-Nitrae-oxazine analog derivative | ZHEJIANG UNIVERSITY (CN) | 2016-04-27 | — | — | CN | disclosed |