Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.63 |
| ▸ | ABL1 | P00519 | 8/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.63 |
| ▸ | BCR | P11274 | 4/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.50 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28827455 | 0.87 | HDAC1 (0.61) | HDAC1HDAC3ABL1HDAC2HDAC4 | |
| SCHEMBL28062146 | 0.83 | HDAC1 (0.58) | HDAC1HDAC3ABL1HDAC2HDAC4 | |
| SCHEMBL27950830 | 0.81 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11KDM4E | |
| SCHEMBL28062115 | 0.81 | HDAC1 (0.57) | HDAC1HDAC3ABL1HDAC2HDAC4 | |
| SCHEMBL27937292 | 0.74 | EGFR (0.53) | MAPK14MAPK13MAPK12MAPK11KDM4E | |
| SCHEMBL2491213 | 0.72 | RAB9A (0.54) | HDAC1HDAC3ABL1HDAC2HDAC4 | |
| SCHEMBL1689283 | 0.72 | HDAC1 (0.58) | HDAC1HDAC3ABL1HDAC2HDAC4 | |
| SCHEMBL774835 | 0.68 | LCK (0.69) | HDAC1ABL1BCRKDRMAPK14 | |
| SCHEMBL18086520 | 0.68 | HDAC1 (0.62) | HDAC1HDAC3ABL1HDAC2HDAC4 | |
| SCHEMBL774476 | 0.68 | MAPK14 (0.84) | ABL1BCRMAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103539793-B | Thiazole carboxamides compounds and application thereof | 南京圣和药业股份有限公司 | 2016-06-08 | — | — | CN | disclosed |