SCHEMBL2806233

SCHEMBL2806233

CCCCN(CCCC)CCCC.Nc1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.50
GAA P10253 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 2/20 0.50
SCN1A P35498 2/20 0.50
SCN2A Q99250 2/20 0.50
SCN3A Q9NY46 2/20 0.50
CHRM2 P08172 2/20 0.50
KCNH2 Q12809 2/20 0.50
DRD3 P35462 2/20 0.50
LMNA P02545 1/20 0.50
HTR1A P08908 1/20 0.50
SLC6A3 Q01959 1/20 0.50
MAPT P10636 5/20 0.46
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 5/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
THRB P10828 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2806230 1.00 CYP3A4 (0.50) CYP3A4GAACYP1A2CYP2D6SCN1A
SCHEMBL2810702 0.83 ALDH1A1 (0.52) CYP3A4GAACYP1A2CYP2D6SCN1A
SCHEMBL2810699 0.83 ALDH1A1 (0.52) CYP3A4GAACYP1A2CYP2D6SCN1A
SCHEMBL8380045 0.80 ALDH1A1 (0.45) CYP3A4GAACYP1A2CYP2D6SCN1A
Phthalic Acid SCHEMBL5875359 0.80 ALDH1A1 (0.55) GAADRD3LMNAMAPTALDH1A1
Phthalic Acid SCHEMBL5875365 0.80 ALDH1A1 (0.55) GAADRD3LMNAMAPTALDH1A1
SCHEMBL231377 0.79 ALDH1A1 (0.68) CYP3A4GAACYP1A2CYP2D6DRD3
SCHEMBL29364937 0.79 ALDH1A1 (0.68) CYP3A4GAACYP1A2CYP2D6DRD3
Aminobenzoic Acid SCHEMBL5875349 0.79 LMNA (0.66) CYP3A4GAACYP1A2CYP2D6SCN1A
SCHEMBL2810654 0.77 ALDH1A1 (0.65) CYP3A4GAACYP1A2CYP2D6DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100240908-A1 ACETYLENE COMPOUND FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
CN-101808982-A Acetylene compound FUJIFILM CORP 2010-08-18 CN disclosed
EP-2202221-A1 ACETYLENE COMPOUND Fujifilm Corporation (JP) 2010-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240908-A1 ACETYLENE COMPOUND NAT1, KATNA1, KAT2B CYP3A4 1909/4885GAA 4079/4885CYP1A2 535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.