SCHEMBL7607464

SCHEMBL7607464

O=C(CCCl)Cc1cccs1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.50
ALDH1A1 P00352 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP2C19 P33261 1/20 0.46
POLB P06746 5/20 0.45
RAB9A P51151 2/20 0.45
USP2 O75604 1/20 0.45
KDM4E B2RXH2 1/20 0.44
PKM P14618 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
GSK3B P49841 1/20 0.43
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062332 0.85 HPGD (0.53) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL1264102 0.85 HPGD (0.53) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7353467 0.84 HPGD (0.60) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL28879909 0.83 TAAR1 (0.53) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL15178187 0.81 HPGD (0.50) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL27593897 0.79 ALDH1A1 (0.52) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL3223780 0.79 HPGD (0.55) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL27482820 0.77 HPGD (0.56) HPGDALDH1A1SMN1; SMN2CYP2C19POLB
SCHEMBL5045391 0.77 HPGD (0.53) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL4775992 0.77 HPGD (0.53) HPGDALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118978890-A Preparation method of single-walled carbon nano antistatic emulsion 浙江纳科纳米新材料有限公司 2024-11-19 CN claimed
CN-118978890-A Preparation method of single-walled carbon nano antistatic emulsion 浙江纳科纳米新材料有限公司 2024-11-19 CN disclosed
CN-118978890-A Preparation method of single-walled carbon nano antistatic emulsion 浙江纳科纳米新材料有限公司 2024-11-19 CN disclosed
EP-1263714-A1 NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES AstraZeneca AB (SE) 2002-12-11 EP disclosed
WO-2001062713-A1 NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES ASTRAZENECA AB (SE) 2001-08-30 WO disclosed
CN-1292698-A Glycine transport inhibitors JANSSEN PHARMACEUTICA NV (BE) 2001-04-25 CN disclosed
EP-1059922-A2 GLYCINE TRANSPORT INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2000-12-20 EP disclosed
WO-1999044596-A2 GLYCINE TRANSPORT INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 1999-09-10 WO disclosed
EP-0707584-A1 NOVEL (1-HETEROAZOLYL-1-HETEROCYCLYL)ALKANE DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE AGENTS Astra Aktiebolag (SE) 1996-04-24 EP disclosed
CN-1029737-C Process for preparing aminoalkylketones derivatives and use in therapy LAFON LABOR (FR) 1995-09-13 CN disclosed
US-5446060-A Aminoalkyl thienyl ketone derivatives and their use as peripheral vasodilators LABORATOIRE L. LAFON (FR) 1995-08-29 US disclosed
EP-0490769-B1 Aminoalkylketone derivatives, process for their preparation and their therapeutical use LAFON LABOR (FR) 1995-04-19 EP disclosed
CN-1062353-A The preparation procedure of new aminoalkyl ketone derivatives and the application in treatment LAFON LABOR (FR) 1992-07-01 CN disclosed
EP-0490769-A1 Aminoalkylketone derivatives, process for their preparation and their therapeutical use LABORATOIRE L. LAFON (FR) 1992-06-17 EP disclosed
EP-0025288-A1 Derivatives of monic acid, processes for their preparation, compositions containing them and their preparation BEECHAM GROUP PLC (GB) 1981-03-18 EP disclosed