Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267384 | 0.82 | BTK (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28033501 | 0.81 | KDM4E (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL15646943 | 0.81 | GABRP (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL13729879 | 0.77 | MAPT (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9692042 | 0.73 | KDM4E (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL13409319 | 0.72 | BTK (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10553536 | 0.71 | TLR8 (0.44) | MAPTCYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL27940119 | 0.71 | CYP1A2 (0.45) | MAPTCYP1A2KDM4ETSHRL3MBTL1 | |
| SCHEMBL21965360 | 0.70 | GABRP (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL15483502 | 0.70 | L3MBTL1 (0.56) | MAPTCYP1A2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103797024-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-06-01 | — | — | CN | disclosed |