SCHEMBL28062906

SCHEMBL28062906

CCCO[Si](CC)(CC)c1cccc(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
ADORA3 P0DMS8 1/20 0.34
MAPT P10636 4/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TP53 P04637 1/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TLR8 Q9NR97 1/20 0.33
CYP3A4 P08684 2/20 0.33
IDO1 P14902 2/20 0.33
AGXT P21549 2/20 0.33
PKM P14618 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17937793 0.90 KMT2A (0.42) KMT2AMAPTALDH1A1KDM4ELMNA
SCHEMBL28062796 0.89 KMT2A (0.37) KMT2AADORA3MAPTMEN1CYP1A2
SCHEMBL17937622 0.86 TRPM8 (0.35) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL28063084 0.86 KMT2A (0.41) KMT2AALDH1A1HPGDTLR8
SCHEMBL28062704 0.83 KMT2A (0.38) KMT2AADORA3MAPTMEN1CYP1A2
SCHEMBL17937665 0.83 KMT2A (0.40) KMT2AADORA3MAPTMEN1CYP1A2
SCHEMBL28062861 0.81 KMT2A (0.39) KMT2AADORA3MAPTMEN1CYP1A2
SCHEMBL17937626 0.81 CYP3A4 (0.35) KMT2ACYP1A2CYP2C9ALDH1A1KDM4E
SCHEMBL28062737 0.80 EGFR (0.39) CYP1A2CYP2C19ALDH1A1KDM4ELMNA
SCHEMBL17937662 0.80 KMT2A (0.41) KMT2AALDH1A1HPGDTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555901-A Polishing composition FUJIMI INC 2016-05-04 CN disclosed