SCHEMBL28062861

SCHEMBL28062861

CCCO[Si](C)(OCCC)c1cccc(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
ADORA3 P0DMS8 1/20 0.34
MAPT P10636 4/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 2/20 0.33
IDO1 P14902 2/20 0.33
AGXT P21549 2/20 0.33
NOTUM Q6P988 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
PTGER1 P34995 1/20 0.33
PKM P14618 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KCNH2 Q12809 1/20 0.33
PNMT P11086 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062833 0.90 KMT2A (0.43) KMT2ACYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL28062714 0.86 CYP3A4 (0.35) KMT2AMAPTMEN1CYP3A4IDO1
SCHEMBL17937665 0.84 KMT2A (0.40) KMT2AADORA3MAPTMEN1CYP1A2
SCHEMBL28062704 0.81 KMT2A (0.38) KMT2AADORA3MAPTMEN1CYP1A2
SCHEMBL28062906 0.81 KMT2A (0.38) KMT2AADORA3MAPTMEN1CYP1A2
SCHEMBL28062796 0.80 KMT2A (0.37) KMT2AADORA3MAPTMEN1CYP1A2
SCHEMBL7132361 0.79 TSHR (0.42) KMT2AMAPTMEN1TP53CYP3A4
SCHEMBL28062847 0.79 EGFR (0.39) CYP1A2CYP2C19IDO1AGXTALDH1A1
SCHEMBL28062839 0.78 ALDH1A1 (0.34) KMT2AMAPTMEN1ALDH1A1
SCHEMBL28063084 0.78 KMT2A (0.41) KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555901-A Polishing composition FUJIMI INC 2016-05-04 CN disclosed