Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10227692 | 0.77 | HDAC4 (0.42) | NPC1HDAC4KDM5BBRD4PDK1 | |
| SCHEMBL10194263 | 0.76 | KDM4E (0.51) | NPC1HDAC4KDM5BBRD4KMT2A | |
| SCHEMBL9451409 | 0.73 | HDAC4 (0.47) | NPC1HDAC4KDM5BBRD4KMT2A | |
| SCHEMBL77337 | 0.73 | HDAC4 (0.47) | NPC1HDAC4KDM5BBRD4KMT2A | |
| SCHEMBL9281044 | 0.73 | HDAC4 (0.54) | NPC1HDAC4BRD4KMT2APDK1 | |
| SCHEMBL2326291 | 0.73 | IDO1 (0.47) | NPC1HDAC4KDM5BBRD4KMT2A | |
| SCHEMBL16628325 | 0.73 | HDAC4 (0.43) | NPC1HDAC4KDM5BBRD4PDK1 | |
| SCHEMBL3462133 | 0.73 | HDAC4 (0.46) | NPC1HDAC4KDM5BBRD4KMT2A | |
| SCHEMBL10558737 | 0.73 | NR1H2 (0.45) | NPC1HDAC4KDM5BBRD4KMT2A | |
| SCHEMBL506494 | 0.72 | ADRB2 (0.47) | HDAC4KDM5BBRD4PDK1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261170-B | Fused heterocyclic compounds and their use for pest control | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |