Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823108 | 0.85 | L3MBTL1 (0.40) | CA1FFAR1FFAR4MAPT | |
| SCHEMBL27915298 | 0.84 | CA1 (0.50) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL27321446 | 0.83 | CA1 (0.57) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL8052116 | 0.83 | CA1 (0.57) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL8994069 | 0.83 | CA1 (0.57) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL15754145 | 0.83 | CA1 (0.57) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| Hydrochloric Acid SCHEMBL27915297 | 0.82 | CA1 (0.48) | CA1ACE2ZDHHC7FAAHFFAR1 | |
| SCHEMBL27743233 | 0.81 | CA2 (0.53) | CA1ZDHHC7FAAHFFAR1GPR84 | |
| SCHEMBL27484669 | 0.81 | CA2 (0.53) | CA1ZDHHC7FAAHFFAR1GPR84 | |
| SCHEMBL1740005 | 0.81 | CA1 (0.59) | CA1ACE2ZDHHC7FAAHFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501264-A | The preparation method of diazabicyclooctane derivative | 明治制果药业株式会社 | 2017-12-22 | — | — | CN | disclosed |
| CN-105555787-B | Process for preparation of diazabicyclooctane derivatives and intermediates therefor | 明治制果药业株式会社 | 2017-08-08 | — | — | CN | disclosed |
| CN-105555787-A | Process for preparation of diazabicyclooctane derivatives and intermediates therefor | MEIJI SEIKA PHARMA CO LT | 2016-05-04 | — | — | CN | disclosed |