Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126661 | 0.84 | P2RY12 (0.51) | SMN1; SMN2POLBALDH1A1HPGDGAA | |
| SCHEMBL15604817 | 0.78 | CA12 (0.42) | POLBALDH1A1GAAKDM4ERAB9A | |
| SCHEMBL1126536 | 0.77 | CNR1 (0.46) | SMN1; SMN2POLBALDH1A1HPGDGAA | |
| SCHEMBL1126573 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2POLBALDH1A1HPGDGAA | |
| SCHEMBL14791059 | 0.76 | CA12 (0.41) | SMN1; SMN2POLBALDH1A1GAAMAPT | |
| SCHEMBL12492750 | 0.76 | CA1 (0.49) | ALDH1A1HPGDNPC1CYP1A2CYP3A4 | |
| SCHEMBL12493994 | 0.75 | BAZ2B (0.44) | SMN1; SMN2ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL15527959 | 0.75 | CA12 (0.43) | SMN1; SMN2POLBALDH1A1GAAMAPT | |
| SCHEMBL3045755 | 0.73 | MAPK1 (0.40) | POLBALDH1A1HPGDGAAMAPT | |
| SCHEMBL16622900 | 0.73 | KDM4E (0.45) | POLBALDH1A1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | disclosed |